Organo-Metalloid Compounds
- (1)
- (19)
- (139)
- (2)
- (10)
- (1)
- (1)
- (27)
- (20)
- (4)
- (62)
- (96)
- (10)
- (1)
- (1)
- (1)
- (1)
- (5)
- (2)
- (1)
- (3)
- (206)
- (153)
- (1)
- (25)
- (23)
- (11)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (251)
- (85)
- (1)
- (1)
- (20)
- (8)
- (9)
- (30)
- (54)
- (3)
- (10)
- (1)
- (8)
- (2)
- (2)
- (8)
- (4)
- (2)
- (21)
- (2)
- (2)
- (3)
- (5)
- (4)
- (4)
- (2)
- (1)
- (3)
- (2)
- (1)
- (5)
- (2)
- (3)
- (1)
- (2)
- (5)
- (4)
- (1)
- (1)
- (3)
- (2)
- (2)
- (2)
- (5)
- (3)
- (3)
- (2)
- (18)
- (3)
- (1)
- (2)
- (4)
- (3)
- (5)
- (1)
- (2)
- (2)
- (2)
- (4)
- (4)
- (1)
- (2)
- (5)
- (6)
- (2)
- (2)
- (4)
- (2)
- (3)
- (4)
- (4)
- (4)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (9)
- (3)
- (4)
- (2)
- (1)
- (1)
- (7)
- (3)
- (5)
- (9)
- (1)
- (3)
- (4)
- (1)
- (7)
- (4)
- (1)
- (4)
- (1)
- (8)
- (1)
- (10)
- (6)
- (3)
- (2)
- (2)
- (4)
- (7)
- (3)
- (2)
- (2)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (5)
- (9)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (2)
- (2)
- (1)
- (1)
- (6)
- (6)
- (1)
- (1)
- (2)
- (5)
- (1)
- (1)
- (1)
- (4)
- (1)
- (4)
- (10)
- (2)
- (4)
- (1)
- (3)
- (6)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (4)
- (3)
- (1)
- (3)
- (3)
- (2)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (8)
- (3)
- (1)
- (4)
- (1)
- (2)
- (2)
- (3)
- (1)
- (3)
- (8)
- (6)
- (1)
- (3)
- (9)
- (2)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (3)
- (6)
- (5)
- (3)
- (1)
- (10)
- (2)
- (5)
- (3)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (8)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (7)
- (3)
- (2)
- (2)
- (8)
- (15)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (4)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (2)
- (2)
- (1)
- (2)
- (1)
- (11)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (2)
- (4)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (3)
- (2)
- (2)
- (4)
- (5)
- (3)
- (4)
- (2)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (5)
- (3)
- (3)
- (5)
- (3)
- (2)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (2)
- (2)
- (3)
- (2)
- (2)
- (1)
- (9)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
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- (4)
- (1)
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- (2)
- (8)
- (2)
- (2)
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- (1)
- (3)
- (1)
- (1)
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- (2)
- (2)
- (5)
- (3)
- (1)
- (20)
- (4)
- (2)
- (2)
- (2)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (4)
- (3)
- (1)
- (3)
- (2)
- (5)
- (1)
- (2)
- (1)
- (4)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (4)
- (2)
- (2)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (4)
- (2)
- (3)
- (3)
- (2)
- (2)
- (2)
- (2)
- (2)
- (4)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (4)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
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- (1)
- (1)
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- (1)
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- (1)
- (4)
- (2)
- (1)
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- (1)
- (1)
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- (1)
- (1)
- (1)
- (1)
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- (2)
- (4)
- (1)
- (14)
- (2)
- (12)
- (1)
- (3)
- (11)
- (2)
- (1)
- (115)
- (4)
- (1)
- (4)
- (2)
- (61)
- (5)
- (1)
- (2)
- (120)
- (15)
- (16)
- (4)
- (2)
- (3)
- (17)
- (177)
- (12)
- (3)
- (1)
- (30)
- (1)
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- (9)
- (1)
- (7)
- (3)
- (3)
- (3)
- (2)
- (2)
- (3)
- (1)
- (1)
- (7)
- (9)
- (19)
- (4)
- (59)
- (5)
- (1)
- (21)
- (3)
- (133)
- (6)
- (122)
- (22)
- (31)
- (5)
- (1)
- (2)
- (6)
- (8)
- (68)
- (2)
- (3)
- (6)
- (5)
- (2)
- (8)
- (2)
- (877)
- (1)
- (1)
- (2)
- (14)
- (2)
- (1)
- (6)
- (8)
- (2)
- (4)
- (3)
- (8)
- (3)
- (1)
- (3)
- (12)
- (1)
- (5)
- (2)
- (4)
- (3)
- (10)
- (4)
- (3)
- (5)
- (2)
- (4)
- (7)
- (8)
- (1)
- (1)
- (1)
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- (3)
- (6)
- (6)
- (3)
- (3)
- (3)
- (10)
- (2)
- (2)
- (6)
- (2)
- (1)
- (4)
- (5)
- (2)
- (4)
- (4)
- (2)
- (4)
- (5)
- (7)
- (5)
- (4)
- (2)
- (6)
- (3)
- (11)
- (12)
- (1)
- (5)
- (2)
- (5)
- (2)
- (10)
- (2)
- (1)
- (3)
- (2)
- (2)
- (2)
- (1)
- (3)
- (6)
- (3)
- (1)
- (2)
- (4)
- (3)
- (4)
- (2)
- (1)
- (2)
- (10)
- (3)
- (3)
- (2)
- (3)
- (2)
- (12)
- (1)
- (3)
- (7)
- (1)
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- (3)
- (3)
- (2)
- (2)
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- (6)
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- (2)
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- (1)
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Filtered Search Results
Aobchem AOBCHEM
5000946206 1- 2-FLUORO-3- TRIMETHYLSILYL
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Aobchem AOBCHEM
5000944227 1 2-DIHYDRO-5- TRIMETHYLSILYL
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Aobchem AOBCHEM
5000942200 2-FLUORO-3- TRIMETHYLSILYL BEN
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Aobchem AOBCHEM
5000937825 2 6-DIFLUORO-3- TRIMETHYLSILYL
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Aobchem AOBCHEM
5000939272 METHYL 5- TRIMETHYLSILYL THIOP
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eMolecules 10416-59-8 | Trimethylsilyl N-(trimethylsilyl)acetimidate | Apollo Scientific US | MFCD00008270 | 203.432 | C8H21NOSi2 | 97.000 | C\C(O[Si](C)(C)C)=N/[Si](C)(C)C | 25g | 726011057
Trimethylsilyl N-(trimethylsilyl)acetimidate | Apollo Scientific US | 10416-59-8 | MFCD00008270 | 203.432 | C8H21NOSi2 | 97.000 | C\C(O[Si](C)(C)C)=N/[Si](C)(C)C | 25g | 726011057
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 38330-80-2 | Monomethyl Potassium Malonate | Accela ChemBio (ASD) | MFCD00014021 | 156.178 | C4H5KO4 | 98.000 | [K+].COC(=O)CC([O-])=O | 100g | 475560689
Monomethyl Potassium Malonate | Accela ChemBio (ASD) | 38330-80-2 | MFCD00014021 | 156.178 | C4H5KO4 | 98.000 | [K+].COC(=O)CC([O-])=O | 100g | 475560689
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eMolecules 78782-17-9 | bis[(pinacolato)boryl]methane | Pharmablock | MFCD27977747 | 267.970 | C13H26B2O4 | 97.000 | CC1(C)OB(CB2OC(C)(C)C(C)(C)O2)OC1(C)C | 2.5g | 686927647
bis[(pinacolato)boryl]methane | Pharmablock | 78782-17-9 | MFCD27977747 | 267.970 | C13H26B2O4 | 97.000 | CC1(C)OB(CB2OC(C)(C)C(C)(C)O2)OC1(C)C | 2.5g | 686927647
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Medchemexpress LLC Abemaciclib (methanesulfonate) | 1231930-82-7 | 99.8% | 602.70 | 200 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This compound is a selective and BBB-permeable inhibitor of CDK4/6, with half-maximal inhibitory concentrations (IC50s) of 2 nM and 10 nM for CDK4 and CDK6, respectively.
- Selective inhibition of key enzymes involved in cell cycle regulation.
- Permeates the blood-brain barrier.
- Reduces cell viability in various human cell lines, including HCT-116, MCF7, and PANC-1.
- Inhibits Rb phosphorylation, leading to a G1 arrest and suppressed proliferation.
- Activity is specific for cells that are proficient in Rb.
- Effective in reducing cell viability across multiple cancer cell lines.
- Demonstrates antiproliferative activity against human HCT116 and MCF7 cells.
- Shows inhibition in resistant cell lines.
- Causes a cooperative antitumor effect when combined with other agents in xenograft models.
- Leads to significant tumor growth inhibition in xenograft models.
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Cambridge Isotope Laboratories 12C Methane QG Diamond 1000L /-5% (12C 99 99% N2 1ppm) CP 99 5% 1000 L
12C Methane QG Diamond 1000L /-5% (12C 99 99% N2 1ppm) CP 99 5% 1000 L
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Selleck Chemical LLC Clobetasol propionate S2584-1g
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Clobetasol propionate (CGP9555 CCl 4725) is an anti-inflammatory corticosteroid used to treat various skin disorders
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Selleck Chemical LLC CHC-A2844-1MG-5
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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CHC is a human monoclonal antibody against clathrin heavy chain (CHC) with potential anti-angiogenesis and anti-tumor activity MW 145 62 KD
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Aobchem AOBCHEM
5000875608 CYCLOPROPYL 4- TRIMETHYLSILYL
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Aobchem AOBCHEM
5000906604 1- 4- TRIMETHYLSILYL PHENYL CY
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Ambeed BIS PINACOLATODIBORANE 100G
NC3847809 BIS PINACOLATODIBORANE 100G
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